http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105169381-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 |
| filingDate | 2015-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105169381-B |
| titleOfInvention | A kind of helicobacter pylori multivalence epitope vaccine and preparation method thereof |
| abstract | The present invention provides a kind of helicobacter pylori polyepitope vaccines, its activity is a polypeptide, is made of urease A and B subunit, adhesin HpaA, the advantage Th of heat shock protein HSP60 and B cell antigen epi-position or section and neutrophil activating protein NAP and b subunit of cholera toxin.The present invention synthesizes an artificial gene by gene synthesis technology, it includes urease A and B subunit, adhesin HpaA, the advantage Th of heat shock protein HSP60 and B cell antigen epi-position or the gene orders of section and neutrophil activating protein NAP, the artificial gene and b subunit of cholera toxin gene are mutually coupled, form a fusion.By the Bacillus coli expression fusion, after protein purification, multivalence epitope vaccine is obtained.The vaccine can excitating organism generate for urease, adhesin HpaA, heat shock protein HSP60 and the T cell immune response of neutrophil activating protein NAP and antibody humoral immune response, it is diseases related available for prevention Helicobacter pylori infection. |
| priorityDate | 2015-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 236.