http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105164126-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2014-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105164126-B |
| titleOfInvention | The Pd catalytic couplings of pyrazole amide |
| abstract | Describe a kind of new method of imidazo [1, the 2 a] pyridine compounds for preparing formula (I), wherein R 1 It is C 1‑4 Alkoxy or NR 4 R 5 , wherein R 4 And R 5 It is independently hydrogen or C 1‑4 Alkyl or R 4 And R 5 Connected nitrogen-atoms formed together can include one it is extra selected from nitrogen or 4 to 6 circle heterocycles of the heteroatomic saturation of oxygen；R 2 It is C 1‑4 Alkyl, C 1‑4 Alkoxy carbonyl group, halogen, optionally by C 1‑4 Alkyl, C 1‑4 The phenyl of alkoxy or halogen substitution, or NR 4 R 5 , wherein R 4 And R 5 It is independently hydrogen or C 1‑4 Alkyl, or R 4 And R 5 Connected nitrogen-atoms formed together can include one it is extra selected from nitrogen or 4 to 6 circle heterocycles of the heteroatomic saturation of oxygen；R 3 It is C 1‑4 Alkyl and X is nitrogen or CH.The imidazo [1 of formula (I), 2 a] pyridine compounds are for use as phosphodiesterase (PDE) inhibitor, the particularly precursor or active component itself of the active component of PDE10 inhibitor, the PDE10 inhibitor has the treatment for example schizoid potentiality (International Patent Publication text WO2012/076430) of neuropsychiatric disorders. |
| priorityDate | 2013-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.