http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105154484-B
Outgoing Links
Predicate | Object |
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classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-66 |
filingDate | 2015-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105154484-B |
titleOfInvention | Method for improving yield of flavobacterium synthetic vitamin K2(MK) by adding inductive substance |
abstract | The invention relates to a method for inducing substance by addingIncrease the synthesis of vitamin K by flavobacterium 2 The yield method specifically comprises the following steps: activating Flavobacterium strain, culturing Flavobacterium seed, fermenting Flavobacterium, centrifuging fermentation liquor, freeze drying, treating methanol, etc., by adding precursor 1, 4-dihydroxy-2-naphthoic acid, precursor analogue VK into fermentation medium 3 Or prenol (YWXC) as an inducer to promote MK biosynthesis, and detecting the obtained extract. The results show that, compared with the control group, the flavobacterium added with the inducing substance synthesizes vitamin K 2 The yield is obviously improved, and vitamin K 2 The dry weight ratio of the yield to the bacteria is greatly improved. The method is simple to operate, strong in controllability, stable in result, safe and environment-friendly. In addition, the yield of MK synthesized by flavobacterium is greatly improved by adding the inducing substance, and a new thought and a new mode are provided for the industrialized large-scale production of vitamin MK. |
priorityDate | 2015-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.