http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105153198-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 |
filingDate | 2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105153198-B |
titleOfInvention | A kind of preparation method of Ceftibuten |
abstract | The invention provides a kind of preparation method of Ceftibuten, including toward adding Cefaclor parent nucleus in reactor, methyltetrahydrofuran and magnesium powder, after reaction disappears to magnesium powder, add appropriate distilled water, stirring, stratification, the drying of organic layer anhydrous magnesium sulfate is separated, after filtering, D301 types weak-base ion-exchange resin and 2 (base of 2 benzyloxycarbonyl amino thiazole 4) penetenoic acids of 5 benzyloxycarbonyl group 2 is added, reacted under uniform temperature and time, after reaction terminates, weak-base ion-exchange resin is filtered, then hydrolyze prepared target product Ceftibuten.The method is a kind of new method for preparing Ceftibuten, and its high income, purity is high, easy to operate, is a production technology for green cleaning, is suitable for the industrialized production of certain scale;And Cefaclor parent nucleus is our company's main product, the technology that Tenth Five-Year Plan Period focus development kind Ceftibuten is our company's sustainable development is prepared using the product of our company. |
priorityDate | 2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.