http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105153110-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06 |
filingDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105153110-B |
titleOfInvention | A kind of synthetic method of Atorvastatin calcium chiral intermediate |
abstract | The invention discloses a kind of synthetic method of Atorvastatin calcium chiral intermediate, belong to the synthesis technical field of medicine intermediate.Technical scheme main points areļ¼ The process route not only avoid danger, severe toxicity, the use of expensive medicine such as butyl lithium, potassium cyanide and periodic acid in chemical synthesis, and because the use of tetra isopropyl oxygen titanium and S dinaphthol mixing chiral catalysts makes the ee of product be worth to effectively improve, the synthetic method raw material is cheap and easy to get, route is simple to operate, it is reproducible and yield is very high, it is adapted to industrialized production. |
priorityDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 675.