http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105147711-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7032 |
| filingDate | 2014-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105147711-B |
| titleOfInvention | A kind of preparation of Fructus Forsythiae active site and its application in prevention and treatment Parkinson's disease |
| abstract | The present invention relates to a kind of preparation methods of conventional Chinese medicine Fructus Forsythiae active site, i.e. after Fructus Forsythiae pulverizing medicinal materials, use water or ethyl alcohol equal solvent refluxing extraction, extracting solution is concentrated to get medicinal extract at reduced pressure conditions, it is extracted by a variety of organic reagents and extracting n-butyl alcohol position organic reagent is recovered under reduced pressure, again through appropriate distilled water dispersing and dissolving, supernatant is taken to be splined on low pole or middle polarity type macroporous absorbent resin, the Fructus Forsythiae active site afforded using water-alcohol system；Chemical component separation and identification are carried out to the active site using a variety of chemical composition separation methods and modern spectroscopy analysis means, 15 compounds have been obtained, wherein 9 noval chemical compounds.Fructus Forsythiae active site in the present invention has the function of significantly inhibiting the neural cell injury of rotenone induction in vitro, can dramatically increase TH positive neuron number in rat substantia nigra dense area caused by rotenone in vivo, improve rat parkinsonian symptoms.Therefore, the drug of prevention and treatment Parkinson's disease can be prepared into. |
| priorityDate | 2014-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.