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publicationDate 2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105143217-A
titleOfInvention Lactam compounds as EP4 receptor selective agonists for the treatment of EP4-mediated diseases and conditions
abstract Compounds of formula (I) are disclosed herein Wherein L 1 , L 2 , L 3 , L 4 , R 1 , R 4 , R 5 , R 6 , and s are as defined in the specification. Compounds of formula (I) are EP4 agonists useful in the treatment of glaucoma, osteoporosis, bone fractures, periodontal bone loss, orthopedic implants, alopecia, neuropathic pain, and related disorders. Pharmaceutical compositions and methods of treating conditions or disorders are also described.
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priorityDate 2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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