http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105131066-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-23 |
| filingDate | 2015-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105131066-B |
| titleOfInvention | A kind of pyrimidine derivatives and preparation method thereof and purposes |
| abstract | A kind of pyrimidine derivatives and preparation method thereof and purposes.The invention discloses I compound represented of formula or its crystal form, salt：Wherein, R 1 Selected from hydrogen, halogen, C 1 ~C 6 Alkyl, C 1 ~C 6 Alkoxy, amino or substituted amino, R 2 ~R 4 Separately or concurrently it is selected from hydrogen, alkali metal, C 1 ~C 6 Alkyl.The SNNP of the compounds of this invention 1 is as pharmaceutical carrier, significantly improve the therapeutic effect of monomer class nucleoside medicine and/or Oligonucleotide drug, with good slow releasing function, enhance the therapeutic effect of drug, reduce drug dose and dosage rate, the bioavilability for improving drug, mitigates the toxic side effect of drug, has good clinical value；Meanwhile preparation method of the invention, have many advantages, such as that high income, purity are high, low energy consumption, step is few, easy to operate, at low cost, environmentally friendly, safe, the application being very suitable in industry. |
| priorityDate | 2015-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.