http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105131064-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 |
filingDate | 2015-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105131064-B |
titleOfInvention | Purposes based on tetrahydrofuran modified nucleotide and its in DNA sequencing |
abstract | The present invention provides a kind of purposes based on tetrahydrofuran modified nucleotide and its in DNA sequencing.The tetrahydrofuran modified nucleotide of the present invention, structural formula is shown in formula I: Such compound synthesis raw material is simple and easy to get, and building-up process is conventional chemical reaction, it is easy to accomplish a large amount of synthesis;And such compound may participate in DNA chain extension, and when template be multiple identical bases under archaeal dna polymerase effect, can only once extend one, extend efficiency almost 100%.In acid condition, connection unit can completely be broken and cut away the fluorescein of mark, and next round extension can equally be carried out with almost 100% efficiency, have the value applied to DNA sequencing. |
priorityDate | 2015-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.