http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105130927-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-112 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-60 |
filingDate | 2015-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105130927-B |
titleOfInvention | One class benzene connection azacyclo- chalcone derivative and its preparation method and application |
abstract | The invention discloses class benzene connection azacyclo- chalcone derivative and its preparation method and application, belong to medicinal chemistry art.The present invention splices nitrogen heterocyclic ring and chalcone parent nucleus skeleton, it is simple efficiently, 12 benzene connection azacyclo- chalcone derivatives of the synthesis of environmental protection.It has following general structure: R 1 For halogen or trimethoxy.R 2 For N methyl piperazines, morpholine, imidazoles, nafoxidine, piperidines.X is halogen or H.Such Compound ira vitro active anticancer experiment shows to Human neuroblastoma cell strain (SK N SH) have certain inhibitory action, can be used as the candidate or lead compound further developed, applied to prepare anti human nerve mother tumor medicine. |
priorityDate | 2015-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.