http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105130895-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2015-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105130895-B |
titleOfInvention | A kind of naphthalimide derivative, its preparation method and application |
abstract | The present invention disclose a kind of naphthalimide derivative, and its preparation method and application, the derivative has a formula Y structure, wherein R be selected from contain heteroatomic hexatomic ring, ‑NHCH 2 CH 2 OH、‑NHCH 2 CH 2 N(CH 3 ) 2 And NHCH 2 CH 2 CH 2 CH 3 In one kind, the hetero atom is N, O, at least one of S atom, it is described contain in heteroatomic hexatomic ring have at least one N atoms, and R is connected by N atoms with the parent nucleus in formula T.The compound of the present invention is prepared by accessing methyl hydrazinocarboxylate in naphthalimide avtive spot, such compound has the activity for suppressing growth to the tumour cell of a variety of different tissue sources such as breast cancer and cervical carcinoma, and it is smaller to the inhibitory activity of human normal cell, suppress to have broad prospects in growth of tumour cell medicine preparing. |
priorityDate | 2015-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.