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filingDate 2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105124349-B
titleOfInvention Application of alpha-lactose in preparation of medicine for preventing and treating acute pancreatitis
abstract The invention discloses application of alpha-lactose in preparation of a medicine for preventing and treating acute pancreatitis, belonging to the field of medicines. Alpha-lactose can reduce inflammatory response by reducing pancreatic tissue edema, serum amylase, pancreatic tissue myeloperoxidase MPO levels during acute pancreatitis; at the same time, the agent can reduce the level of inflammatory mediators, such as MCP-1 and TNF-alpha, in pancreatic tissue and pancreatic acinar cells; in addition, the substance has the effects of inhibiting the activation of extracellular regulatory protein kinase (ERK 1/2 MAPK) and nuclear factor kappa B (NF-kappa B) protein signal channels, reducing the infiltration of immune cells such as neutrophils and macrophages in pancreatic tissues and having a remarkable protective effect on acute pancreatitis.
priorityDate 2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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