http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105124349-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7016 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L21-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L29-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-17 |
filingDate | 2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105124349-B |
titleOfInvention | Application of alpha-lactose in preparation of medicine for preventing and treating acute pancreatitis |
abstract | The invention discloses application of alpha-lactose in preparation of a medicine for preventing and treating acute pancreatitis, belonging to the field of medicines. Alpha-lactose can reduce inflammatory response by reducing pancreatic tissue edema, serum amylase, pancreatic tissue myeloperoxidase MPO levels during acute pancreatitis; at the same time, the agent can reduce the level of inflammatory mediators, such as MCP-1 and TNF-alpha, in pancreatic tissue and pancreatic acinar cells; in addition, the substance has the effects of inhibiting the activation of extracellular regulatory protein kinase (ERK 1/2 MAPK) and nuclear factor kappa B (NF-kappa B) protein signal channels, reducing the infiltration of immune cells such as neutrophils and macrophages in pancreatic tissues and having a remarkable protective effect on acute pancreatitis. |
priorityDate | 2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.