http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105106944-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate | 2015-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105106944-B |
| titleOfInvention | Angiotensin converting enzyme 3（ACE3）Function and application in myocardial hypertrophy is treated |
| abstract | The invention discloses a kind of angiotensin converting enzyme 3（ACE3）Function and application in myocardial hypertrophy is treated, belong to the function and application field of gene.Present invention determine that the correlation between the expression of ACE3 and myocardial hypertrophy, result of study shows in the model that myocardial hypertrophy occurs, and the expression of ACE3 and normally organizes to compare and significantly reduces；Suppress ACE3 expression and significantly promote myocardial hypertrophy, fibrosis, deteriorate heart function, promote ACE3 to be overexpressed and then significantly suppress myocardial hypertrophy, fibrosis, protect heart function.Therefore; ACE3 can be used as target gene; for screening cardioprotection function, anti-cardiac fibrosis and/or prevention, alleviation and/or the medicine for treating myocardial hypertrophy; cardioprotection function, resisting cardiac hypertrophy and/or prevention, alleviation and/or the medicine for treating myocardial hypertrophy are used to prepare, an effective new way is provided for the treatment of myocardial hypertrophy. |
| priorityDate | 2015-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 371.