http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105106168-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 |
| filingDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105106168-B |
| titleOfInvention | A kind of esomeprazole magnesium intestines capsule and preparation method thereof |
| abstract | The invention discloses a kind of esomeprazole magnesium capsulae enterosolubilis and preparation method thereof, esomeprazole magnesium is prepared into enteric-coated micro-pill, then micropill is packed into gastric-dissolved capsule and is prepared.The enteric-coated micro-pill of the present invention is made up of blank capsule core, drug-loaded layer, two layers of separation layer, enteric layer and film-coating layer.To ensure the stability of medicine, alkaline material is added in blank capsule core；Alkaline stabiliser and antioxidant are added in drug-loaded layer；The conditioning agent that alkalescence is higher and alkalescence is relatively low is separately added into two layers of separation layer.To ensure that result of extraction adds surfactant in enteric layer, while the stability of film-coating layer raising product is packed in outer layer.Optimized by the formulation and technology of micropill, improve the stability of product, improve the smoothness of technique, improve operating efficiency, shorten Coating times, reduce drain on manpower and material resources, reduce production cost. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3875522-A4 |
| priorityDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.