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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14
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filingDate 2015-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6aa95577257e21a2e9c617263ec38668
publicationDate 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105106132-A
titleOfInvention Pharmic tadalafil composition granules for treating urological diseases
abstract The invention discloses pharmic tadalafil composition granules for treating urological diseases, and belongs to the technical field of medicament. A composition is prepared from tadalafil, saccharose, glucose, glycine, polyethylene glycol and purified water. The tadalafil is a novel crystal-type compound, an X-ray powder diffraction pattern measured through a Cu-K alpha-ray is shown in graph 1, and the tadalafil is different from that reported in the prior art; according to experiments, it is found that the compound with the novel crystal-type structure has significantly improved water solubility and is low in impurity content and good in stability; the granules prepared from the novel crystal-type tadalafil compound is good in stability, low in impurity content and high in bioavailability, and the safety of clinical applications is improved.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106432281-A
priorityDate 2015-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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