http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105087469-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate | 2015-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105087469-B |
| titleOfInvention | The method that external evoked fat mesenchymal stem cell breaks up to mature hepatocytes |
| abstract | The invention belongs to technical field of bioengineering, and in particular to a kind of method that external evoked adipose-derived mescenchymal stem cell (ADSCs) breaks up to mature hepatocytes (iHeps).This method includes the steps that are as follows: isolates ADSCs；External evoked culture ADSCs breaks up to iHeps, and induction atomization is divided into 3 stages: entoderm induction period；At liver induction period；The stage of ripeness of liver cell.Use method of inducing differentiation of the invention, it is only necessary to which nine days or so time just generated the liver cell with liver cell form, gene expression and function enough, was shortest hepatocyte differentiation method of current used time.This is beneficial to the application of clinical treatment. |
| priorityDate | 2015-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.