http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105085419-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-24 |
filingDate | 2015-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105085419-B |
titleOfInvention | A kind of synthetic method of pyrazine compounds |
abstract | Synthetic method the present invention relates to provide pyrazine compounds shown in a kind of lower formula (III), methods described includes:In to organic solvent, in the presence of catalyst, accelerator and acid additive, lower formula (I) compound and formula (II) compound are reacted, so as to obtain the formula (III) compound, Wherein, R 1 It is C 1 ‑C 6 Alkyl or phenyl;R 2 、R 3 It is each independently selected from H, C 1 ‑C 6 Alkyl, halogen or phenyl.Methods described by the appropriately selected of catalyst, accelerator, acid additive and organic solvent with combine, purpose product is obtained such that it is able to high yield, and the reaction time is short, reaction temperature is low, it is easily controllable, preferable reaction effect is reached, especially medicine intermediate synthesis field has a good application prospect and industrial production potential in organic synthesis field. |
priorityDate | 2015-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.