http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105079814-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2014-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105079814-B |
titleOfInvention | A kind of realgar of modified with folic acid-mesoporous monox nanometer combination drug |
abstract | For nanometer-size realgar, to normal cell, there is also this defects of certain toxic side effect, the present invention modifies folic acid in mesoporous monox nanometer particle surface, realgar is loaded again, it is intended to improve its active targeting in vivo, and in particular to a kind of realgar mesoporous monox nanometer combination drug of modified with folic acid and preparation method thereof.The volume ratio that the present invention passes through investigation ethylenediamine and water, the concentration of realgar ethylenediamine solution, carrier amount and load time are found, the mesoporous monox nanometer particle of modified with folic acid has realgar certain load capacity, form the realgar mesoporous monox nanometer combination drug of modified with folic acid, and its pattern and structure do not occur significantly to change, but it targets characteristic and need to also be verified further across In vitro cell experiment. |
priorityDate | 2014-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.