http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105064045-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M101-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M15-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M15-15 |
| filingDate | 2015-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105064045-B |
| titleOfInvention | Method for carrying out enzymatic fibroin functional modification based on grafted polypeptide |
| abstract | The invention discloses a method for carrying out enzymatic fibroin functional modification based on grafted polypeptide. Serine in silk fibroin is catalytically oxidized through an enzyme to generate reactive aldehyde, and is grafted with polypeptide containing tyrosine; the number of tyrosine residues on the fibroin surface is increased; subsequent tyrosinase catalytic fibroin is promoted to react with a functional amino compound; the enzymatic modification efficiency of silk fibroin is improved; and a multifunctional fibroin material is built. The method comprises the following specific steps: (1) treating the fibroin material in a laccase/4-oxo-2,2,6,6-tetramethyl piperidine-1-oxyl (TEMPO) system; (2) grafting the polypeptide containing tyrosine on the surface of the fibroin material; and (3) reacting the tyrosinase catalytic fibroin with the functional amino compound. Compared with a traditional chemical cross-linking method for preparing a functional fibroin material, the method has the advantages of high enzyme catalysis efficiency and mild enzyme treatment condition; and the performance of the fibroin material is obviously improved. |
| priorityDate | 2015-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.