http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105061652-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F120-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-34 |
| filingDate | 2015-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105061652-B |
| titleOfInvention | A kind of preparation method of DNA polymer hollow microsphere |
| abstract | The invention discloses the preparation method of a kind of DNA polymer hollow microsphere, the steps include: to prepare poly-N N-isopropylacrylamide (PNIPAAm) first with light-initiated controllable free-radical polymerisation method；Then hexamethylene diamine, DNA with EDC are reacted and prepare aminated dna；Amidized DNA and Traut ' s Reagent reagent reacting is obtained sulfhydrylation DNA；Again sulfhydrylation DNA with PNIPAAm is reacted and prepare DNA poly-N N-isopropylacrylamide coupling body；Finally shake after co-emulsifier, emulsifying agent, DNA poly-N N-isopropylacrylamide coupling body, buffer, the mixing of oil phase certain proportion, prepare DNA polymer (DNA PNIPAAm) tiny balloon.Synthesis step of the present invention is simple, and easy to operate, thus it is possible to vary processing conditions changes Microsphere Size, microsphere itself has preferable biocompatibility in addition, shows wide application prospect at aspects such as tissue engineering material, medicament slow release and beauty treatments. |
| priorityDate | 2015-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.