http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105061459-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 2015-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105061459-B |
| titleOfInvention | A kind of preparation method of bisulfate clopidogrel I crystal spheroidal crystal |
| abstract | Instant invention overcomes single solvent and be difficult to prepare the technical difficulty of spheroidal crystal, use single solvent 2 butanol, by controlling to add amount and the particle diameter of bisulfate clopidogrel I crystal crystal seed, make bisulfate clopidogrel with the stable precipitation from solution system of spheroidal crystal of specific powder morphology scope, gained bisulfate clopidogrel spheroidal crystal has specific powder property, it is in more excellent state, the beneficially realization of powder vertical compression preparation process at aspects such as dissolvent residual, bulk density and mobility.The present invention further discloses a kind of pharmaceutical composition comprising and using present invention process to prepare bisulfate clopidogrel I crystal spheroidal crystal. |
| priorityDate | 2015-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.