http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105061283-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B41-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B41-12 |
| filingDate | 2015-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105061283-B |
| titleOfInvention | The preparation method of amino-acid benzyl ester hydrochloride |
| abstract | It is catalyst in suitable solvent using metal chloride the invention discloses a kind of preparation method of amino-acid benzyl ester hydrochloride, amino acid and Mr. hydrogen chloride are into amino acid hydrochloride salt, then, it is esterified at a reflux temperature with phenmethylol, generation water is taken out of by azeotropic, promotes esterification, after the completion of reaction, thermal response liquid is filtered, so as to remove catalyst, then low pressure removing low-boiling-point substance (solvent), through last handling processes such as recrystallizations, target product amino-acid benzyl ester hydrochloride is obtained.Recycling Mother Solution after recrystallization is applied mechanically, and cycle-index is more than 5 times.This method have the advantages that cost of material is relatively low, conversion ratio is higher, post processing compared with it is simple, do not need chlorinating agent, the three waste discharges such as thionyl chloride less, suitable for industrialized production. |
| priorityDate | 2015-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.