http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105056915-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-30 |
filingDate | 2015-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105056915-B |
titleOfInvention | A kind of preparation and application of aptamer modified magnetic metal organic framework medium |
abstract | The invention belongs to material science and modern separation analysis field, it is related to a kind of preparation method and application of the magnetic metal organic framework medium of novel nucleic acids aptamers modification, step is as follows:Nano level amino functional magnetic ferroferric oxide (NH is prepared first 2 ‑Fe 3 O 4 ), then using hydrothermal synthesis method synthesizing magnetic metal organic framework medium, finally use coupling agent Streptavidin to prepare the aptamer modified medium of magnetic metal organic framework 101 of Ochratoxin A (OTA Apt MMIL 101) for intermediate.Using ferroso-ferric oxide and 3 aminopropyl triethoxysilanes (APTES) reacting functionalization, by NH 2 ‑Fe 3 O 4 With medium (MIL 101) synthetic agent of metal organic framework 101 under hydrothermal reaction condition, chemical bonding synthesis OTA Apt MMIL 101 are washed, vacuum drying.The OTA Apt MMIL 101 of the present invention have stability good and high selectivity recognition performance, it is adaptable to the selective enrichment separation of the complex sample such as biological, environment and food. |
priorityDate | 2015-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.