http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105055380-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c6ed83b9d5c28c6c356d1d08d58501e7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-05 |
| filingDate | 2015-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b2562c31e35c5d2279f814159976108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f57c6d293dd8e028df21e0ae8ad1e23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86882eef43a2ec844ef357247ef6a15c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e978a716030272ba7bd0cde289cb59d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7b4a5aae1c0e3d9f7928498277eb874 |
| publicationDate | 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105055380-A |
| titleOfInvention | Application of totarol to preparation of drug for preventing and treating ischemic cerebral apoplexy |
| abstract | The invention belongs to the field of pharmaceuticals and relates to application of totarol serving as a natural product extracted from podocarpus totara to preparation of a drug for preventing and treating ischemic cerebral apoplexy. A result obtained by researching glutamic acid of rat cortex neurons, a hypoxia and hypoglycemia model and a rat middle cerebral artery occlusion experimental model shows that the totarol can be used for reducing neurotoxicity caused by glutamic acid, reducing neuron injury caused by hypoxia and hypoglycemia, improving the activity of glutathione peroxidase in cortical neurons and brain tissues and the activity of superoxide dismutase, reducing the volume of cerebral ischemia infarct caused after cerebral apoplexy and improving the scores of neurological behaviors. The result proves that the totarol has a remarkable neuroprotective effect for ischemic brain tissues and can be used for preparing a drug for preventing and treating ischemic cerebral apoplexy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114044764-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112618395-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112618395-B |
| priorityDate | 2015-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.