http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105017346-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 |
| filingDate | 2015-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105017346-B |
| titleOfInvention | Three or six branched sugared p-methoxyphenyl glucosides of mannopentaose six and preparation method and application |
| abstract | The present invention provides sugared p-methoxyphenyl glucosides of the branched mannopentaose six of one kind three or six and preparation method and application.Its structural formula is as shown in Formulas I or formula II：Application of the compound in inverase and treatment AIDS-treating medicine is prepared.The present invention is from mannose; using rational synthesis strategy; disaccharide and four saccharide acceptors are synthesized first; then the mannopentaose and the sugar of sweet dew six of full guard are respectively obtained using the condensation of Schmidt glycosidations, the mannopentaose and the sugar of sweet dew six obtain target pentasaccharides and six sugar compounds after deprotection.Appropriate blocking group is cleverly introduced in reaction designing, whole course of reaction is efficiently carried out, and it is easy to operate.Study of pharmacy shows：Compound shown in formula I or formula II has the significant activity of AntiHIV1 RT activity 1, can be used as potentially treating AIDS-treating medicine. |
| priorityDate | 2015-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 141.