abstract |
Polyfluorinated compounds are used as Bruton's tyrosine kinase inhibitors, and the present invention provides new polyfluorinated substituted pyrazolopyrimidine compounds or salts shown in formulas (I) and (II), their preparation methods, and the use of these Compounds and their formulations for the treatment and inhibition of autoimmune diseases or disorders, heteroimmune diseases or disorders, inflammatory diseases and methods of cancer or disorders. |