http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105017114-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-08 |
| filingDate | 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105017114-B |
| titleOfInvention | Preparation method of 1-isopropyl-3-tert-butylthiourea |
| abstract | The invention discloses a preparation method of 1-isopropyl-3-tert-butylthiourea. Ammonium thiocyanate, tert-butyl alcohol and hydrochloric acid serve as raw materials and conduct the substitution reaction to generate a mixture of thiocyanic acid tert-butyl ester and isothiocyanic acid tert-butyl ester, the mixture stands still and is layered, water in the mixture is removed, then concentrated sulfuric acid serves as a transposition catalyst, thiocyanic acid tert-butyl ester is transposed to generate isothiocyanic acid tert-butyl ester, finally under the existence of isopropylamine, water serves as a solvent, the addition reaction is conducted, and a target product is synthesized. Water is removed in the reaction based on the principle that the specific gravity of matter is reduced to different degrees along with increase of temperature, and a large amount of heat energy is saved; the sulfuric acid serves as the transposition catalyst, and the reaction yield is increased to more than 90% from about 66% originally; the water serves as the solvent, risks are reduced in the production process of a production workshop, operation is safer, environment friendliness is achieved, cost is low, and quality is high; the total reaction yield of the method can be more than 88.9% by ammonium thiocyanate, and the method is more suitable for industrial production. |
| priorityDate | 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.