http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105016963-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50ada4dd961b92a30c5d988b417da962 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-02 |
| filingDate | 2014-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6219c5109958809fd819b5d5b92ec844 |
| publicationDate | 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105016963-A |
| titleOfInvention | A kind of synthetic method of 2-bromo-5-iodotoluene |
| abstract | The invention discloses a synthesis method of 2-bromo-5-iodotoluene. Using o-toluidine as the starting material, the product can be obtained by iodization and diazotization of bromine. Wherein the iodination step uses iodine powder as the iodination reagent, sodium percarbonate as the oxidant, and ethyl acetate/glacial acetic acid mixed solution as the solvent. The diazotization and bromination steps are completed by a one-pot method, using sodium nitrite and hydrobromic acid as reaction reagents, and copper powder/cuprous bromide as bromination catalyst. The advantages of using this process route to synthesize 2-bromo-5-iodotoluene are: the raw materials in the iodination step are safe and easy to obtain, the process is easy to operate, the reaction conditions are mild, the conversion rate of raw materials is high, and the total molar yield of iodine atoms can reach 72%. The above; the diazotization and bromination steps are combined and completed in one pot, which is easy to operate and has few by-products. After the hydrobromic acid is treated, it can be used mechanically for many times, which saves costs and is more environmentally friendly. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113214041-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113233957-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113233957-A |
| priorityDate | 2014-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.