| abstract |
The object of the present invention is to provide a novel organophosphorus ligand that can efficiently carry out cross-coupling reactions and obtain the target product in a high yield, and further provide fine-tuning of steric and electronic properties, and by using the above-mentioned substances, it can be obtained at a high yield. Yield of the manufacturing method for the cross-coupling reaction. As a solution, a phosphine compound represented by the following general formula (1) is provided, (In the formula, R 1 and R 2 each independently represent a secondary alkyl group, a tertiary alkyl group or a cycloalkyl group, R 3 and R 4 each independently represent a hydrogen atom, an aliphatic group, a heteroaliphatic group, an aromatic group, Alicyclic group or heterocyclic group. In addition, R 3 and R 4 do not have a phosphorus atom, and R 3 and R 4 are not hydrogen atoms at the same time. |