http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105002188-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2015-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105002188-B |
| titleOfInvention | A kind of heat-resisting regulation and control method of microorganism intelligence step |
| abstract | In fermentation process, the growth and production of microorganism frequently suffer from the limitation of heat stress.For the purpose of building thermotolerant coliform chassis host, this patent creates a kind of heat-resisting regulation and control method of microorganism intelligence step using synthesis application of biological method, the heat resistance of microorganism can be improved in two aspects of cell and flora, it mainly includes step refractory system and quantity regulator control system.Step refractory system includes the heat-resisting function element such as heat shock protein (HSPs), ubiquitin and transcription factor, is combined as controlling element with the RNA temperature-sensitive switches of engineer and promoter, it is possible to achieve the step of microorganism is heat-resisting.Micro organism quantity regulator control system is dynamically turned on profit his property programmed cell death system, efficiently controls metabolic heat, the ability that microorganism adapts to heat stress is improved in flora aspect then using intervention school-based and RNA temperature-sensitive switches are combined as and door switch.By the synergy of two systems, adaptability and robustness of the microorganism to specific high temperature and high temperature fluctuations are improved. |
| priorityDate | 2015-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.