http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105002178-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2015-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105002178-B |
| titleOfInvention | Suppress STAT3 expression and prevent and treat shRNA and the application of chronic graft versus host disease |
| abstract | It can effectively suppress STAT3 gene expressions the present invention relates to one and prevent and treat the shRNA of chronic graft versus host disease, and provide STAT3 shRNA to mice spleen CD4 + CD62L + The influence of cell differentiation, act on mouse bone marrow cells CD117 + The security of early stage stem/progenitor cells, and the therapeutic action to murine chronic graft versus host disease(GVH disease) (cGVHD) model：Influence after being acted on including STAT3 shRNA to Th17/Treg ratios, cGVHD clinical scores and target organ pathological score.Research for the progress preventing and treating mankind cGVHD in living animal provides experimental basis.For developing, new anti-cGVHD medicines and raising cGVHD therapeutic effect have great importance. |
| priorityDate | 2015-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 350.