http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105001114-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 |
| filingDate | 2014-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105001114-B |
| titleOfInvention | Prepare the new method of Iopromide |
| abstract | The present invention relates to the preparation methods of Iopromide, provide three new methods for preparing Iopromide：Method one：It is starting material with formula II, reacts to obtain formula III with allylamine, formula III reacts to obtain formula IV with N- methyl allyl amine, and formula IV reacts to obtain formula V with methoxyacetyl chloride, and formula V obtains Iopromide formula I through peroxidating；Method two：It is starting material with formula II, reacts to obtain formula III with allylamine, formula III reacts to obtain formula IV -1 with methoxyacetyl chloride, and formula IV -1 reacts to obtain formula V with N- methyl allyl amine, and formula V obtains Iopromide formula I through peroxidating；Method three：It is starting material with formula II, reacts to obtain formula III with allylamine, formula III reacts to obtain formula IV -1 with methoxyacetyl chloride, and formula IV -1 reacts to obtain formula V -1 with 3- methylamino -1,2-PD, and formula V -1 obtains Iopromide formula I through peroxidating；Method four：It is starting material with formula II, reacts to obtain formula III -1 with methoxyacetyl chloride, formula III -1 reacts to obtain formula IV -1 with allyl amine, and formula IV -1 reacts to obtain formula V with N- methacrylic amine, and formula V obtains Iopromide formula I through peroxidating. |
| priorityDate | 2014-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.