http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104997819-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f2c23a543ebe192f369de8d3d8d9180 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00 |
| filingDate | 2015-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a2d65ed28834656266f8fa40c24b0d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_460c93380cd4463edcce41b32e7a0b9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c562644d6ebe996136b4974b598ff80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d914a41f45cefe3a806b96e8151648f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec7b16849d15e8c1165f3b0c5bac8c67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b9174db8b70e5f7404d69be0dd92ee1 |
| publicationDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104997819-A |
| titleOfInvention | Application of storax and cell bath lotion mixture in restraining Kir2.1 outward currents |
| abstract | The invention discloses application of a storax and cell bath lotion mixture in restraining Kir2.1 outward currents. The mixture comprises storax and cell bath lotion, and the volume ratio of the storax to the cell bath lotion is 1:10-500. The pH value of the cell bath lotion ranges from 7.2 to 7.4, and osmotic pressure is adjusted to range from 290 mOsm/L to 310 mOsm/L through saccharose. The mixture is used for hatching cells of mutant D172N and E299V channel protein with Kir2.1 expressed, and the outward currents can be effectively restrained. The ratio of restraining the outward currents of Kir2.1 single-point mutant D172N and E299V is 100 percent through the mixture of the storax and the cell bath lotion, the half effective inhibition concentrations are 0.01653 and 0.01224 (the volume ratio of the storax and the cell bath lotion), and a door is opened for studying effective therapeutic of short QT3 syndromes. |
| priorityDate | 2015-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.