http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104997727-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 |
filingDate | 2015-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104997727-B |
titleOfInvention | A kind of curcumin micella nasal-cavity administration solution and preparation method thereof |
abstract | The invention discloses a kind of curcumin micella nasal-cavity administration solution, it is main ingredient and preservative, isotonic regulator including curcumin, it is excipient substance characterized by further comprising Polyvinylcaprolactame polyvinyl acetate ethylene glycol copolymer, medical polyethylene glycol class auxiliary material and RGD peptide, curcumin main ingredient and Polyvinylcaprolactame polyvinyl acetate ethylene glycol copolymer excipient substance mass ratio are 1:12~1:Between 20, medical polyethylene glycol class auxiliary material and Polyvinylcaprolactame polyvinyl acetate ethylene glycol copolymer excipient substance mass ratio are 1:20~1:Between 40, RGD peptide and medical polyethylene glycol class auxiliary material mass ratio are 1:2~1:Between 4.Curcumin micella nasal-cavity administration solution prepared by the present invention, so that curcumin has good dissolving its preparation method in aqueous, not only solve the water solubility of curcumin, improve curcumin stability of molecule, while micella particle diameter is adjusted to suitable particle size range(150~220nm), improve the stability of micellar aqueous solution. |
priorityDate | 2015-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.