http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104994924-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-884 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-20 |
filingDate | 2013-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104994924-B |
titleOfInvention | Use the replacement stationary phase purified organic compound on reversed-phase column |
abstract | Only two kinds increases can be in single run by way of preparing high-efficient liquid chromatography of oppisite phase (preparative RP HPLC) is come the amount of the sample purified:(1) traditional approach is to use larger post (larger amount of stationary phase);And (2) use the displacement chromatography for more effectively utilizing stationary phase.Present invention description uses unique preparative RP HPLC technologies of the silica of the derivatizations of C 18/C 8, the silica of the derivatizations of C 18/C 8 is coated with hydrophobicity quaternary ammonium salt Huo quaternary alkylphosphonium salts, to cause compared with conventional preparative RP HPLC technologies, (including the crude mixture of the organic compound of the rough peptide of synthesis) 7 to 12 times of sample load increase.This increase of sample load capacity and output is due to that the additional replacement for the quaternary salt that C 18/C 8 are combined fixes phase behaviour.Quaternary surfactant is incorporated in the chains of C 18/C 8 and silanol of stationary phase. |
priorityDate | 2013-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.