http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104987325-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
filingDate | 2015-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104987325-B |
titleOfInvention | A kind of preparation method of voriconazole |
abstract | The present invention relates to a kind of preparation method of voriconazole, comprises the steps:1) compound A reacts to obtain compound B with 10 sulfonic acid chloride of D Camphoras, and 2) compound B Jing bromos obtain compound C;3) compound C is condensed to obtain compound 6 with compound 5;4) 6 Jing palladium carbon catalytic hydrogenations of compound obtain voriconazole.Synthetic method of the present invention is easy to operate, and stereo selectivity is high, and raw material is easy to get, and cost is relatively low.RSO2Cl is 10 sulfonic acid chloride of D Camphoras. |
priorityDate | 2015-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.