http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104983687-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2015-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104983687-B |
| titleOfInvention | A kind of Nano medication and preparation method with oncotherapy effect |
| abstract | The invention discloses a kind of Nano medication and preparation method with oncotherapy effect.It is first with hollow mesoporous silica nano-particle（HMSNs）Adriamycin is loaded, then is handled with bicarbonate, that is, " nano bomb " is made.After medicine enters Cytolysosome by endocytosis, the H in lysosome + Can with drug response, produce CO rapidly 2 Gas；The gas breaks of the generation integrality of lysosome or the permeability for improving lysosome membrane, the induction cell death related to lysosome, so as to killing cancer cell.It is somebody's turn to do " nano bomb " also to have a good therapeutic effect to persister, can effectively overcomes the drug resistance of cancer cell. |
| priorityDate | 2015-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.