http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104975023-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate | 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104975023-B |
| titleOfInvention | Human cervical carcinoma shifts relevant new long-chain non-coding RNA sequence, separation method and application thereof |
| abstract | The present invention relates to human cervical carcinomas to shift relevant new long-chain non-coding RNA sequence, available for the target sequence of RNA interference, the short hairpin of coded interference target spot and RNAi target sequences, shRNA short hairpin nucleic acid sequence recombinant vectors and recon containing long-chain non-coding RNA sequence, and the invention further relates to separation methods of the new long-chain non-coding RNA sequence and application thereof.The long-chain non-coding RNA sequence base of the present invention is by bioinformatics method, expands to obtain by RACE from the relevant cDNA library of cervical carcinoma, by being sequenced, hybridizing, the experiments such as cell Proliferation, cell invasion, demonstrates function of the RNA sequence and application thereof；RNAi shRNA, siRNA sequence and the recombinant vector of the sequence-specific are designed, and demonstrates the function of siRNA, shRNA.Long-chain non-coding RNA sequence provided by the invention, RNAi disturbance target points, the short hairpins of shRNA are of great significance on the early diagnosis and therapy of cervical carcinoma. |
| priorityDate | 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.