http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104974168-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-08 |
filingDate | 2014-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104974168-B |
titleOfInvention | The preparation method of asenapine and the intermediate for being used to prepare asenapine |
abstract | The present invention relates to the intermediates that asenapine is prepared shown in the method for preparing asenapine shown in general formula (11) and general formula (8).Described method includes following steps: obtaining general formula (9) compound represented by ring-closure reaction by general formula (8) compound represented;General formula (10) compound represented is obtained by reduction reaction by general formula (9) compound represented;And asenapine shown in general formula (11) is obtained by substitution reaction as general formula (10) compound represented.In general formula (8), R 1 Represent halogen, preferably chlorine or bromine. |
priorityDate | 2014-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.