abstract |
The present invention provides a multi-substituted pyridine compound represented by formula I, its preparation method, use and pharmaceutical composition: The multi-substituted pyridine compound represented by formula I of the present invention has excellent anti-tumor effect, can simultaneously inhibit various cell kinases, and has obviously excellent pharmacokinetic characteristics, and is very suitable for oral and intravenous administration. The pharmaceutical composition of the present invention can be used to treat tumors and cancers. |