http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104974123-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 2015-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104974123-B |
| titleOfInvention | Coumarin kind compound with antioxidation activity and preparation method and application |
| abstract | The invention belongs to pharmaceutical technology field, the application of more particularly to a kind of coumarin kind compound with antioxidation activity and preparation method thereof and such compound in for neuroprotection, antitumor, anticoagulation, radioresistance and antiinflammatory action medicine preparation；Coumarin kind compound has following general structure： Wherein, R 1 ,R 2 For one kind in H, alkyl, alkoxy, hydroxyl, halogen, nitro, cyano group, carboxylic acid and its ester.The present invention is using ethanol or acetic acid as solvent, under the catalysis of ammonium acetate, is cured the blue hydrocarbon Azulene of wound by 4 Hydroxycoumarins and its substituent, 1 cyanogen acetyl group and the component reaction of aromatic aldehyde three is made.Preparation method of the present invention is simple to operate, and target product yield is high, free radical is acted on stronger elimination, suitable for large-scale production. |
| priorityDate | 2015-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.