| abstract |
The invention discloses compounds of formula (I) and salts thereof, wherein: a) R 1 is H or -CH 3 and R 2 is R y ; or b) R 1 is R x and R 2 is H; wherein R x and Ry is as disclosed in this application. The invention also discloses the method of using these compounds to inhibit Notch receptors, and the pharmaceutical composition containing these compounds. These compounds are prodrugs of compounds that are useful in the treatment, prevention or slowing of the progression of diseases or disorders such as cancer in various fields of medicine. |