| abstract |
The invention discloses a method for synthesizing N-arylamide compounds by utilizing amides and aniline compounds. The synthesis method is: use palladium salt and ligand as catalyst, mix N,N-dimethylformamide compound, aniline compound, protonic acid, Lewis acid and organic solvent, and heat reaction to obtain N-arylamide compound. The invention has the advantages of short preparation route, good substrate universality, mild reaction conditions, high synthesis yield, simple and easy-to-obtain raw materials and catalysts, and the like. |