http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104945457-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-056 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104945457-B |
| titleOfInvention | 1‑（1 ', 3 ', 4 ', 6 '-four O acetyl group α/β D glucopyanosyls）4 contraposition substituted aryl [1,2,3] triazoles and its preparation method and application |
| abstract | With antitumor activity 1（1 ', 3 ', 4 ', 6 '-four O acetyl group α/β D glucopyanosyls）The preparation and its application of 4 contraposition substituted benzyl epoxide methyl [1,2,3] triazole series compounds, its core texture is substitution of 1,2,3 triazole derivatives on Isosorbide-5-Nitrae.Above-claimed cpd has good inhibitory activity to rectum cancer cell.It can be used as the medicine of the anti-carcinoma of the rectum.The synthetic method of above-claimed cpd includes：The preparation of the O acetyl group D glucose intermediates of 2 nitrine 1,3,4,6；The preparation of 4 contraposition substituted aryl base propargyl ethers；Click-reaction generation 1 occurs under monovalence copper catalysis in a solvent for the O acetyl group D glucose intermediate of 2 nitrine 1,3,4,6 and 4 contraposition substituted aryl propargyl ethers（1 ', 3 ', 4 ', 6 '-four O acetyl group α/β D glucopyanosyls）4 contraposition substituted benzyl epoxide methyl [1,2,3] triazole series compounds. |
| priorityDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.