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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54326
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
filingDate 2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f494e2305494721e1dd7d5a9e3677b56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37393166a29a25fda558d9be8e2bdeb6
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publicationDate 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104931691-A
titleOfInvention Method for coupling carboxyl microspheres with amino
abstract The invention provides a method for coupling carboxyl microspheres with amino and belongs to the technical field of preparation of in-vitro diagnosis kits. 4-(4,6-dimethoxy triazin-2-yl)-4-methylmorpholine hydrochloride serves as a cross-linking agent, microspheres of which the surface is coupled with carboxyl can be efficiently coupled with the amino, the whole process is simple and convenient to operate, reaction conditions are mild and not severe, the pH value of a buffer solution ranges from 4.5 to 9.0, the coupling efficiency is high, and the usage of reagents is low. The invention provides new application of the cross-linking agent, the cross-linking agent is applied to the technical field of coupling of the carboxyl microspheres with the amino for the first time, and the microspheres coupled with the amino are applied to a latex turbidity method and a chemiluminescence method for protein detection; a detection result shows that main performance indexes meet requirements, the usage of the reagents is reduced, the cost is saved, the operation is simplified, and the market application prospect and the economic value are greater.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114460310-A
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priorityDate 2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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