http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104928265-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-865 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
| filingDate | 2014-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104928265-B |
| titleOfInvention | A kind of Ketoreductase mutant and its preparation and application |
| abstract | The invention discloses a kind of Ketoreductase mutant and its preparation and application.A kind of Ketoreductase mutant gene, nucleotide sequence is as shown in SEQ ID NO.1.The Ketoreductase mutant of the gene code, amino acid sequence is as shown in SEQ ID NO.2.The present invention has compared with high specific (enantiomeric excess value by chemistry, molecular biology, bioinformatics and high-throughput screening method, the Ketoreductase mutant of exploitation>And preferable catalytic activity 99.9%), itself and hydrogenlyase (FDH) and NADH are used in conjunction with, for asymmetric reduction 2 [3 [3 (2 (quinolyl of 7 chlorine 2) vinyl] phenyl] 3 oxopropyls] methyl benzoate to be to prepare (S, E) methyl 2 [3 [3 (2 (base of 7 chloroquinoline base 2) vinyl] phenyl] 3 hydroxypropyls] t-butyl perbenzoate. |
| priorityDate | 2014-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.