http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104928249-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 |
filingDate | 2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104928249-B |
titleOfInvention | A kind of internal construction method of sarcoma180 multidrug resistance cell strain |
abstract | The present invention provides a kind of internal construction method of sarcoma180 multidrug resistance cell strain, belongs to field of biomedicine technology.From cis-platinum, three kinds of medicine vivo medicine-feedings of fluorouracil and endoxan and gradually incremental dose induction S180 ascites tumor mouse, successfully construct S180 multidrug resistance cell strains, there is cross resistance to adriamycin, resistance intensity is higher, and resistance stabilization time is longer.The present invention is research tumor multi-medicine drug-resistant mechanism, each series antineoplastic medicament of screening, tumor drug resistance reversal medicine of the research and development including Chinese medicine or crude drug species provide mouse tumor multidrug resistance cell strain and animal model, with good application prospect. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107937483-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107937483-B |
priorityDate | 2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.