http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104926867-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e74277852f1aae0a3ff13f59a65456d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6553 |
| filingDate | 2015-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20d0df244c99bb8dc965b6fe9fa24346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ff257f8f3037bbe25d8731c65020057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac02915d96113999debaaa6ed766decb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ad91af4e969e4388f0015d41a91136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_104eb1cd81cfaa8bfd1c433faca7001a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7825f09eb335c03921c3857efd191574 |
| publicationDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104926867-A |
| titleOfInvention | A kind of preparation method of alkenyl phosphoester compound |
| abstract | The invention discloses a preparation method of an alkenyl phosphoester compound, using palladium acetate or tetrakis(triphenylphosphine) palladium as a catalyst, base, ligand, diazo compound and halide or base, p-toluenesulfonyl hydrazone and The halide reacts in an organic solvent under the protection of N 2 atmosphere to obtain the alkenyl phosphoester compound RR'C=C(Ar)(P(O)(OMe) 2 ), wherein: Ar represents a substituted or unsubstituted aromatic radicals, including phenyl, naphthyl and heterocycle; R and R'represent substituted or unsubstituted aryl, alkyl, alkenyl or hydrogen. The reaction involved in the method of the present invention can successfully obtain the alkenyl phosphoester compound of the E configuration, the operation is convenient and simple, and has good tolerance and universality to the functional group, while the amount of the catalyst is small, and the reagent and the solvent are not used. Special treatment is required, the reaction cost is low, and it can be widely used in the preparation of alkenyl phospholipids. |
| priorityDate | 2015-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.