abstract |
The present invention provides a compound for treating tumors and its application, and provides the compound represented by formula I or a pharmaceutically acceptable salt thereof. The compound provided by the invention has high drug peak concentration, high drug absorption and long elimination half-life, which can improve the drug efficacy in clinical use and reduce the frequency of administration. The compound prepared by the present invention or a pharmaceutically acceptable salt thereof can be used as a PARP inhibitor drug, and has certain antitumor activity, especially for triple negative, primary or metastatic breast cancer, colon cancer, uterine cancer, Pancreatic cancer, lung cancer, gastric cancer, blood cancer, melanoma, solid tumor or intracranial tumor have good therapeutic activity, which provides a new option for clinical drug use. |