http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104922689-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 |
| filingDate | 2015-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104922689-B |
| titleOfInvention | Antitumor polymer bond drug a kind of biodegradable and with pH responses and preparation method thereof |
| abstract | The invention discloses antitumor polymer bond drug a kind of biodegradable and with pH responses and preparation method thereof；The preparation method of antitumor polymer bond drug is to trigger the lactide of the side base containing ENB to carry out polymerisation with the polylactide containing poly glycol monomethyl ether side chain, obtains macromolecule carrier polymer；Macromolecule carrier polymer carries out sulfydryl alkene luminous point with hydrosulphonyl functionalized antineoplastic and hits chemical reaction, that is, obtains antitumor polymer bond drug, and the preparation method is simple to operate, reaction condition is gentle, and side reaction is few, and yield is high；And obtained antineoplastic polymer bond drug biological degradability is very good, and there is pH responses, drugloading rate is big and controllable；Purity is high；Antitumor polymer bond drug is nontoxic, available for clinical trial. |
| priorityDate | 2015-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.